TB Dictionary

Along with Alberto Garcia-Basteiro and many others, Marcel co-piloted the creation and editing of the Global TB Dictionary, a consensus TB dictionary to unify the language we speak.

Since its launch in 2024, the TB Dictionary has had 23,000 views by 2,900 total users.

  

Alberto L Garcia-Basteiro, Joanna Ehrlich, Maryline Bonnet, Marianne Calnan, Stephen M Graham, Sabine Hermans, Adriana Jarrett, Rhoda Lewa, Anna Mandalakas, Leonardo Martinez, Giovanni Battista Migliori, Catherine WM Ong, Larissa Otero, Molebogeng Xheedha Rangaka, Mario CB Raviglione, Barbara Seaworth, Willy Ssengooba, Grant Theron, Anete Trajman, Marcel A Behr. Lancet Global Health, The, 2024-05-01, Volume 12, Issue 5, Pages e737-e739, Copyright © 2024 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license


BCG strains that are mono-resistant to drugs used for TB

Sarah Danchuk has engineered a panel of recombinant BCG strains that are mono-resistant to drugs used for TB. Strains available by request or also deposited at the BCCM/ITM Mycobacteria collection.

  

Danchuk S, McIntosh F, Jamieson FB, May K, Behr MA. . Clinical Microbiology and Infection, 2020 Mar; 26(3): 384.e5-384.e8 

The rBCG strains have been used in Sarah N Danchuk, Ori E Solomon, Thomas Andreas Kohl, Viola Dreyer, Ivan Barilar, Christian Utpatel, Stefan Niemann, Dick van Soolingen, Richard Anthony, Jakko van Ingen, Joy S Michael, Marcel A Behr. Thorax. 2024 Jun 14;79(7):670-675. doi: 10.1136/thorax-2023-220202.


Ancestral sequence for the Mycobacterium tuberculosis complex

Luke Harrison has imputed the ancestral sequence for the Mycobacterium tuberculosis complex, called MTBC 0. The sequence can also be accessed via Mycobrowser.

  

Harrison LB, Kapur V, Behr MA. . Microb Genom. 2024 Jan;10(1):001165. doi: 10.1099/mgen.0.001165.PMID: 38175684


Previous work

Graphical user interface for Genomic Sequence Comparison

MycoHit is a JAVA application

This program serves to perform BLAST searches then parses the TBLASTN result files with PERL scripts in order to select the highest score for each protein. Obtained data, including the score, are then stored on a local MYSQL database. It was first published in :

Veyrier F, Pletzer D, Turenne C, Behr MA.. BMC Evol Biol. 2009 Aug 10;9:196. doi: 10.1186/1471-2148-9-196.

Contact

Contact lynn.derycapes [at] mail.mcgill.ca (Lynn Dery Capes) if you wish to receive a zipped copy of the files and instructions for this application.